Mining terabytes of submillimeter-resolution ECoG datasets for neurophysiologic biomarkers

TitleMining terabytes of submillimeter-resolution ECoG datasets for neurophysiologic biomarkers
Publication TypeConference Paper
Year of Publication2010
AuthorsJ Viventi, J Blanco, and B Litt
Conference Name2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Date Published12/2010
Abstract

Recent research in brain-machine interfaces and devices to treat neurological disease indicate that important network activity exists at temporal and spatial scales beyond the resolution of existing implantable devices. We present innovations in both hardware and software that allow sampling and interpretation of data from brain networks from hundreds or thousands of sensors at submillimeter resolution. These innovations consist of novel flexible, active electrode arrays and unsupervised algorithms for detecting and classifying neurophysiologic biomarkers, specifically high frequency oscillations. We propose these innovations as the foundation for a new generation of closed loop diagnostic and therapeutic medical devices, and brain-machine interfaces. © 2010 IEEE.

DOI10.1109/IEMBS.2010.5627681